著 書

1. Hattori Y, Matsuda N. Protection from lethal cell death in cecal ligation and puncture-induced sepsis mouse model by in vivo delivery of FADD siRNA. In:Targets in Gene Therapy. ed. by Yongping You. pp.409-422, InTech-Open Access Publisher 2011.

総 説

1. Hatakeyama N and Matsuda N. Alert Cell Strategy: Mechanisms of Inflammatory Response and Organ Protection. Curr Pharm Des 20: 5766-5778, 2014.

2. Matsuda N. Alert cell strategy in SIRS-induced vasculitis: sepsis and endothelial cells. J Intensive Care 4:21, 2016.

英 文 原 著

1. Matsuda N, Teramae H, Yamamoto S, Takano KI, Takano Y, Hattori Y. Increased death receptor pathway of apoptotic signaling in septic mouse aorta: effect of systemic delivery of FADD siRNA. Am J Physiol Heart Circ Physiol 298;92-101, 2010.

2. Matsuda N, Teramae H, Futatsugi M, Takano KI, Yamamoto S, Tomita K, Suzuki T, Yokoo H, Koike K, Hattori Y. Regulation of histamine H4 receptors contributes to splenic apoptosis in septic mice: counteraction of the anti-apoptotic action of nuclear factor-kB. J Pharmacol Exp Ther 109;1635-1643, 2010.

3. Zhang XH, Yokoo H, Nishioka H, Fujii H, Matsuda N, Hayashi T, Hattori Y. Beneficial effect of the oligomerized polyphenol oligonol on high glucose-induced changes in eNOS phosphorylation and dephosphorylation in endothelial cells. Br J Pharmacol 159, 928–938, 2010

4. Tange K, Kinoshita H, Minonishi T, Hatakeyama N, Matsuda N, Yamazaki M, Hatano Y. Cerebral oxygenation in the beach chair position before and during general anesthesia. Minerva Anestesiologica 76:485-490, 2010

5. Haba M, Hatakeyama N, Kinoshita H, Teramae H, Azma T, Hatano Y, Matsuda N. The modulation of vascular ATP-sensitive K+ channel function via phosphatidylinositol 3-kinase-Akt pathway activated by phenylephrine. J Pharmacol Exp Ther 334:673-678, 2010

6. Tange K, Kinoshita H, Hatakeyama N, Minonishi T, Matsuda N. Warming of cristalloid fluid can alter accuracy of the containing volume level due to changes in the counter's shape. Circ Cont 31:131-137, 2010

7. Takano KI, Yamamoto S, Tomita K, Takashina M, Yokoo H, Matsuda N, Takano Y, Hattori Y. Successful Treatment of Acute Lung Injury with Pitavastatin in Septic Mice: Potential Role of Glucocorticoid Receptor Expression in Alveolar Macrophages. J Pharmacol Exp Ther 336:381-90, 2011

8. Miyamichi R, Mayumi T, Asaoka M, Matsuda N. Evaluating patient self-assessment of health as a predictor of hospital admission in emergency practice: a diagnostic validity study. Emerg Med J 2011 Jul 27
宮道先生 2011年度 学位論文 名古屋大学大学院 救急・集中治療医学分野

9. Aoki Y, Hatakeyama N, Yamamoto S, Kinoshita H, Matsuda N, Hattori Y, Yamazaki M. Role of ion channels in sepsis-induced atrial tachyarrhythmias in guinea pigs. Br J Pharmacol 166:390-400,2011

10. Kageyama S, Yokoo H, Tomita K, Kageyama-Yahara N, Uchimido R, Matsuda N, Yamamoto S, Hattori Y. High glucose-induced apoptosis in human coronary artery endothelial cells involves up-regulation of death receptors. Cardiovasc Diabetol. 2011 Aug 4;10:73.

11. Kimura-Kuroiwa K, Adachi YU, Mimuro S, Kawamata M, Sato S, Matsuda N. Pentobarbital decreased nitric oxide release in the rat striatum but ketamine increased the release independent of cholinergic regulation. Exp Anim 2012;61:165-70, 2012

12. Kinoshita H, Matsuda N, Iranami H, Ogawa K, Hatakeyama N, Azma T, Kawahito S, Yamazaki M. Isoflurane pretreatment preserves adenosine triphosphate-sensitive k+ channel function in the human artery exposed to oxidative stress caused by high glucose levels. Anesth Analg 115:54-61, 2012

13. Kimura-Kuroiwa K, Adachi YU, Obata Y, Kawamata M, Sato S, Matsuda N. Dexmedetomidine and hydroxyzine synergistically potentiate the hypnotic activity of propofol in mice. J Anesth 26:422-8,2012

14. Matsuno K, Iwata K, Matsumoto M, Katsuyama M, Cui W, Murata A, Nakamura H, Ibi M, Ikami K, Zhang J, Matoba S, Jin D, Takai S, Matsubara H, Matsuda N, Yabe-Nishimura C. NOX1/NADPH oxidase is involved in endotoxin-induced cardiomyocyte apoptosis. Free Radic Biol Med 53:1718-1728, 2012.

15. Oda S, Aibiki M, Ikeda T, Imaizumi H, Endo S, Ochiai R, Kotani J, Shime N, Nishida O, Noguchi T, Matsuda N, Hirasawa H; Sepsis Registry Committee of The Japanese Society of Intensive Care Medicine.
The Japanese guidelines for the management of sepsis. J Intensive Care 2:55, 2014.

16. Tochikubo J, Matsuda N, Ota Y, Higashi T, Takatani Y, Inaba M, Adachi Y, Shiiya N. Detection of inflammatory circulating endothelial cells using human umbilical vein endothelial cells detached from culture dishes by tumor necrosis factor-alpha as control cells. Cardiol Pharmacol 2014;4:129.
栃久保先生 2015年度 学位論文 浜松医科大学(研究生・共同研究支援:名古屋大学大学院 救急・集中治療医学分野)

17. Yamamoto S, Niida S, Azuma E, Yanagibashi T, Muramatsu M, Huang TT, Sagara H, Higaki S, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Hamashima T, Mori H, Matsuda N, Ishii Y, Sasahara M. Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes. Sci Rep 5:8505, 2015.

18. Wang Q, Yokoo H, Takashina M, Sakata K, Ohashi W, Abedelzaher LA, Imaizumi T, Sakamoto T, Hattori K, Matsuda N, Hattori Y. Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages. Crit Care Med 43:e508-520, 2015.

19. Nishikimi M, Matsuda N, Matsui K, Takahashi K, Ejima T, Liu K, Ogura T, Higashi M, Umino H, Makishi G, Numaguchi A, Matsushima S, Tokuyama H, Nakamura M, Matsui S. CAST: a new score for early prediction of neurological outcomes after cardiac arrest before therapeutic hypothermia with high accuracy. Intensive Care Med 42:2106-2107, 2016.

20. Inaba M, Matsuda N, Banno H, Jin W, Wachino JI, Yamada K, Kimura K, Arakawa Y. In vitro reduction of antibacterial activity of tigecycline against multidrug-resistant Acinetobacter baumannii with host stress hormone norepinephrine. Int J Antimicrob Agents 48:680-689, 2016.
稲葉先生 2016年度 学位論文 名古屋大学大学院 救急・集中治療医学分野

21. Hattori M, Yamazaki M, Ohashi W, Tanaka S, Hattori K, Todoroki K, Fujimori T, Ohtsu H, Matsuda N, Hattori Y. Critical role of endogenous histamine in promoting end-organ tissue injury in sepsis. Intensive Care Med Exp 4:36, 2016.


1. Nishiyama K, Ohta Y, Matsuda N, Fujimoto R, Koike K. Back pain after wild mushroom consumption. Emerg Med J 27:61, 2010

2. Minonishi T, Kinoshita H, Tange K, Hatakeyama N, Matsuda N, Azma T, Hatano Y. Tracheal intubation with the AirwayScope videolaryngoscope using straight vs curved reinforced tubes. Can J Anaesth 57:92-93, 2010.

3. Kinoshita H, Matsuda N. Issues Regarding Propofol Concentrations within the Clinical Range. Anesthesiology 114:218, 2011

4. Hosono K, Matsumura N, Matsuda N, Fujiwara H, Sato Y, Konishi I. Successful recovery from delayed amniotic fluid embolism with prolonged cardiac resuscitation. J Obstet Gynaecol Res 37:1122-5, 2011.

5. Kinoshita H, Matsuda N. The effect of insulin may not be so simple. Anesthesiology 116:488, 2012

6. Adachi YU, Tuzuki M, Matsuda N.Is it constantly possible to penetrate only the anterior vessel wall against hydrostatic strain? Crit Care Med 40:2534-5, 2012

7. Adachi YU, Matsuda N. Epidural catheter insertion during general anesthesia. J Anesth 26:633, 2012

8. Kinoshita H, Matsuda N. The effect of insulin may not be so simple. Anesthesiology 116:489-490, 2012

9. Adachi YU, Matsuda N. Is it fluid or air causing anesthesia mumps? J Anesth 26:638-639, 2012.

10. Murata T, Kubodera T, Ohbayashi M, Murase K, Adachi YU, Matsuda N. Recurarization after sugammadex following a prolonged rocuronium infusion for induced hypothermia. Can J Anaesth 60:508-509, 2013.

11. Adachi YU, Hatano T, Hashimoto S, Ejima T, Murase K, Matsuda N. The advanced radial artery cannulation using Insyte-A™ with real-time ultrasound guidance. J Clin Monit Comput. 27:703-704, 2013.

12. Suzuki K, Numaguchi A, Adachi YU, Obata Y, Hatano T, Ejima T, Sato S, Matsuda N.
Continuous administration of landiolol reduced QT dispersion in postoperative patients. J Clin Anesth. 26:438-442, 2014.

13. Adachi YU, Numaguchi A, Matsuda N. Not only bupivacaine but also propofol is sinking in lipid? J Anesth. 28:476, 2014.

14. Tochikubo J, Adachi YU, Ejima T, Numaguchi A, Matsuda N, Sato S, Shiiya N. Landiolol reduces hemodynamic responses to bronchoscopy-assisted suctioning in intubated ICU patients. J Intensive Care. 2014 Jan 23;2:6

15. Tochikubo J, Adachi YU, Ejima T, Numaguchi A, Matsuda N, Sato S, Shiiya N. Landiolol reduces hemodynamic responses to bronchoscopy-assisted suctioning in intubated ICU patients. J Intensive Care. 2:6, 2014.

16. Numaguchi A, Adachi YU, Aoki Y, Ishii Y, Suzuki K, Obata Y, Sato S, Nishiwaki K, Matsuda N. Radial artery cannulation decreases the distal arterial blood flow measured by power Doppler ultrasound. J Clin Monit Comput. 2014 Dec 16.

17. Adachi YU, Numaguchi A, Matsuda N. Ultrasonography-guided radial artery catheterization and further optimal sequences. J Clin Monit Comput. 29:201-202, 2015.

18. Matsuda N, Yamada S, Hinoshita T, Sasaki J, Ikeda H, Harunari N, Sakamoto T. The International Activities in Taiwan by the Joint Burn Care Assistance Team of Physicians from Japan Medical Association and Three Medical Societies. JMAJ 59:12-16, 2016.